It is VERY inportant to back up your computer files. But, most non-profits and small businesses I know struggle with how to backup their files and computers, what to back up and how often to back up.
Here is a great article by TechSoup, a reliable resource for all things technical. The article lays out ways to choose the hardware and your software that best meets your need, as well as, tons of other useful information to get you started or improve your current system.
http://www.techsoup.org/learningcenter/techplan/page12379.cfm?cg=btc&sg=...